A multi-purpose laboratory light box for observation and photographic procedures comprises a box of convenient size having two slidable top panels adapted to be moved toward and away from each other to provide an opening of variable width and location. The box is covered with light-absorbing black material inside and out. A pair of tubular fluorescent lamps are mounted respectively within the box on the facing edge portions of the two top panels, the lamps being adjacent the panels and substantially flush with the facing edges of the panels. In use, the lamps are energized to provide light in the variable opening between the top panels for purposes of observing and photographing desired characteristics of various laboratory specimens. Fluorescent lamps of different characteristics such as white light and ultraviolet light are useable interchangeably, depending on requirements. An invertible panel member covered with black velvet material on one face and white reflecting material on the other face may be used on the interior box bottom to provide light absorption or light reflection, depending on the requirements for a particular observation or photographic procedure. Plate members of various light-transmitting materials are provided to rest on the top panels and overlie the illuminated opening between the panels.

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